One of my favorite media apps is VLC by VideoLAN but when I tried to use it in Vista it would kill the Areo Glass feature; something about video incompatibility or some such.

While browsing around for other stuff though I ran across a tip that said to change the Video output module to OpenGL (Preferences -> Video -> Output Modules — with Advanced Options enabled)

I am happy to report that it works great and I am back using one of my favorite apps.